We evaluated the virucidal activity of two quaternary ammonium compounds (QAC) disinfectants…. Two QAC disinfectants are highly effective for the inactivation of SARS-CoV-2, which makes them practical for use in healthcare settings and laboratories where prompt disinfection is important.  The low-level disinfectant based on amphoteric surfactant, W30, which may present in commonly available household hygiene agents is also able to inactivate SARS-CoV-2.